MOLECULAR AND CELLULAR BIOLOGY OF LENTIVIRAL VECTOR-MEDIATED GENE TRANSFER AND EXPRESSION

Pubblicazioni Scientifiche

• 2005 HUMAN GENE THERAPY

  Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses

• 2005 CELL

  Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

• 2004 VIROLOGY

  Molecular evidence of inefficient transduction of proliferating human B lymphocytes by VSV-pseudotyped HIV-1-derived lentivectors

• 2005 MOLECULAR THERAPY

  Efficient Tet-dependent expression of human factor IX in vivo by a new self-regulating lentiviral vector

• 2004 Blood

  Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

• 2005 HUMAN GENE THERAPY

  Gene therapy for a mucopolysaccharidosis type I murine model with lentiviral-IDUA vector

• 2003 Blood

  Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

• 2004 CANCER CELL

  Targeting the tumor and its microenvironment by a dual-function decoy Met receptor

• 2005 BIOCHEMICAL JOURNAL

  Treatment of the mouse model of mucopolysaccharidosis type IIIB with lentiviral-NAGLU vector

• 2004 JOURNAL OF CLINICAL INVESTIGATION

  An uncleavable form of pro-scatter factor suppresses tumor growth and dissemination in mice

• 2005 CANCER GENE THERAPY

  RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis

• 2005 NATURE BIOTECHNOLOGY

  Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters

• 2005 MOLECULAR THERAPY

  Axons mediate the distribution of arylsulfatase A within the mouse hippocampus upon gene delivery

• 2003 Nucleic acids research

  Deletion in a (T)(8) microsatellite abrogates expression regulation by 3 '-UTR

• 2005 HUMAN GENE THERAPY

  Gene therapy of storage disorders by retroviral and lentiviral vectors

• 2003 HUMAN GENE THERAPY

  In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors

• 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME

  Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors