CONSTITUTIVE AND REGULATED EXPRESSION OF NORMAL AND MUTATED HUNTINGTIN IN ST14A STRIATAL CELLS: BIOLOGICAL AND BIOCHEMICAL ASPECTS
- 3 Anni 1999/2002
- 134.279€ Totale Fondi
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Pubblicazioni Scientifiche
- 2002 HUMAN MOLECULAR GENETICS
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
- 2003 NEWS IN PHYSIOLOGICAL SCIENCES
Dysfunction of wild-type Huntingtin in Huntington disease
- 2000 JOURNAL OF NEUROSCIENCE
Wild-type Huntingtin protects from apoptosis upstream of caspase-3
- 2001 FASEB JOURNAL
Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin
- 2003 NATURE GENETICS
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
- 2001 SCIENCE
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
- 2002 JOURNAL OF BIOLOGICAL CHEMISTRY
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons
- 2001 JOURNAL OF BIOLOGICAL CHEMISTRY
Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing
- 2000 HUMAN MOLECULAR GENETICS
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells