IN VIVO GENE THERAPY PROTOCOLS TO REPAIR CNS DAMAGE IN METACHROMATIC AND GLOBOID LEUKODYSTROPHIES

Pubblicazioni Scientifiche

• 2005 JOURNAL OF NEUROSCIENCE RESEARCH

  Myelin deterioration in twitcher mice: Motor evoked potentials and magnetic resonance imaging as in vivo monitoring tools

• 2006 JOURNAL OF NEUROSCIENCE

  Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy

• 2004 JOURNAL OF NEUROSCIENCE RESEARCH

  Analysis of galactocerebrosidase activity in the mouse brain by a new histological staining method

• 2006 DEVELOPMENTAL NEUROSCIENCE

  Cerebellar neurons and glial cells are transducible by lentiviral vectors without decrease of cerebellar functions

• 2008 DEVELOPMENTAL NEUROSCIENCE

  Multipotential neural precursors transplanted into the metachromatic leukodystrophy brain fail to generate oligodendrocytes but contribute to limit brain dysfunction

• 2009 JOURNAL OF NEUROSCIENCE RESEARCH

  Combined Hematopoietic and Lentiviral Gene-Transfer Therapies in Newborn Twitcher Mice Reveal Contemporaneous Neurodegeneration and Demyelination in Krabbe Disease

• 2006 JOURNAL OF NEUROSCIENCE

  Neural stem/progenitor cells participate in the regenerative response to perinatal hypoxia/ischemia

• 2003 DEVELOPMENTAL NEUROSCIENCE

  Notch1 and Numb genes are inversely expressed as oligodendrocytes differentiate

• 2004 NEUROCHEMICAL RESEARCH

  Embryonic expression of the soma-restricted products of the myelin proteolipid gene in motor neurons and muscle

• 2006 DEVELOPMENTAL NEUROSCIENCE

  Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury