INVESTIGATION OF SODIUM CHANNEL INACTIVATION PROPERTIES PUTATIVELY CORRELATED WITH THE PHYSIOPATHOLOGY OF HEREDITARY MYOPATHIES

Pubblicazioni Scientifiche

• 1998 BIOPHYSICAL JOURNAL

  Activation and inactivation of homomeric KvLQT1 potassium channels

• 1999 JOURNAL OF GENERAL PHYSIOLOGY

  The muscle chloride channel ClC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia

• 1999 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

  Myopathic mutations affect differently the inactivation of the two gating modes of sodium channels

• 2000 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

  Functional properties of sodium channels do not depend on the cytoskeleton integrity

• 1998 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

  Fast- and slow-gating modes of the sodium channel are altered by a paramyotonia congenita-linked mutation

• 1999 JOURNAL OF GENERAL PHYSIOLOGY

  The block of Shaker K+ channels by kappa-conotoxin PVIIA is state dependent

• 2000 FEBS LETTERS

  Endogenous expression of the beta 1A sodium channel subunit in HEK-293 cells

• 1998 EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

  Calcium dependent shifts of Na+ channel activation correlated with the state dependence of calcium-binding to the pore

• 1999 BIOPHYSICAL JOURNAL

  Tonic and phasic tetrodotoxin block of sodium channels with point mutations in the outer pore region

• 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

  Inactivation defects produced by a myopathic II-S6 mutation of the muscle sodium channel