MOLECULAR MECHANISMS OF NEURONAL CELL DEATH INDUCED BY NEUROTOXIC PRION PROTEIN FRAGMENTS: PHYSICO-CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF A MINI-PRION PEPTIDE (PRP89-231)
- 3 Anni 1999/2002
- 123.950€ Totale Fondi
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Pubblicazioni Scientifiche
- 2002 NEUROCHEMISTRY INTERNATIONAL
Expression in E-coli and purification of recombinant fragments of wild type and mutant human prion protein
- 2002 NEUROBIOLOGY OF DISEASE
p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells
- 2000 NEUROBIOLOGY OF DISEASE
Apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126
- 2003 JOURNAL OF NEUROCHEMISTRY
Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic
- 2000 INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126
