MOLECULAR PATHOLOGY OF MALIGNANT HYPERTHERMIA: DOES THE ARGININE 615 CYSTEINE MUTATION OF THE RYANODINE RECEPTOR CAUSE THE DISEASE?

Pubblicazioni Scientifiche

• 1994 BIOCHEMISTRY

  IDENTIFICATION AND CHARACTERIZATION OF 3 CALMODULIN-BINDING SITES OF THE SKELETAL-MUSCLE RYANODINE RECEPTOR

• 1996 ANESTHESIOLOGY

  Chlorocresol, an additive to commercial succinylcholine, induces contracture of human malignant hyperthermia-susceptible muscles via activation of the ryanodine receptor Ca2+ channel

• 1995 BIOCHEMISTRY

  CALMODULIN-BINDING SITES OF THE SKELETAL, CARDIAC, AND BRAIN RYANODINE RECEPTOR CA2+ CHANNELS - MODULATION BY THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN-KINASE

• 1995 MOLECULAR PHARMACOLOGY

  A RYANODINE RECEPTOR-LIKE CA2+ CHANNEL IS EXPRESSED IN NONEXCITABLE CELLS

• 1994 EXPERIMENTAL CELL RESEARCH

  APOPTOSIS IS DEPENDENT ON INTRACELLULAR ZINC AND INDEPENDENT OF INTRACELLULAR CALCIUM IN LYMPHOCYTES

• 1994 BIOCHEMICAL JOURNAL

  ALTERATION OF INTRACELLULAR CA2+ TRANSIENTS IN COS-7 CELLS TRANSFECTED WITH THE CDNA-ENCODING SKELETAL-MUSCLE RYANODINE RECEPTOR CARRYING A MUTATION ASSOCIATED WITH MALIGNANT HYPERTHERMIA