RETROVIRAL TRANSFER OF GALACTOCEREBROSIDASE (GALC) CDNA TO MURINE OLIGODENDROCYTES PROGENITOR CELLS:A PRELUDE TO GENE THERAPY FOR KRABBE DISEASE
- 2 Anni 1999/2001
- 92.962€ Totale Fondi
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Pubblicazioni Scientifiche
- 1999 NEUROCHEMICAL RESEARCH
Transduction of cultured oligodendrocytes from normal and twitcher mice by a retroviral vector containing human galactocerebrosidase (GALC) cDNA
- 2002 GLIA
Stage-specific gene expression in early differentiating oligodendrocytes
- 2004 NEUROCHEMICAL RESEARCH
Activation of cell cycle regulatory proteins in the apoptosis of terminally differentiated oligodendrocytes
- 2000 MOLECULAR GENETICS AND METABOLISM
Krabbe disease: Genetic aspects and progress toward therapy
- 2001 NEUROBIOLOGY OF DISEASE
Retrovirus-mediated gene transfer and galactocerebrosidase uptake into twitcher glial cells results in appropriate localization and phenotype correction