THE MOLECULAR BASIS OF CARDIAC DYSFUNCTION IN THE LONG QT SYNDROME

Pubblicazioni Scientifiche

• 1996 CIRCULATION RESEARCH

  Differential response to Na+ channel blockade, beta-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome

• 1995 EMBO JOURNAL

  C-TERMINUS DETERMINANTS FOR MG2+ AND POLYAMINE BLOCK OF THE INWARD RECTIFIER K+ CHANNEL IRK1

• 1995 PHARMACOLOGICAL RESEARCH

  Pharmacological implications of inward rectifier K+ channels regulation by cytoplasmic polyamines

• 1995 CIRCULATION RESEARCH

  CLONED HUMAN INWARD RECTIFIER K+ CHANNEL AS A TARGET FOR CLASS-III METHANESULFONANILIDES

• 1995 CIRCULATION

  LONG QT SYNDROME PATIENTS WITH MUTATIONS OF THE SCN5A AND HERG GENES HAVE DIFFERENTIAL RESPONSES TO NA+ CHANNEL BLOCKADE AND TO INCREASES IN HEART-RATE - IMPLICATIONS FOR GENE-SPECIFIC THERAPY