INDENTIFICATION OF DOWNSTREAM TARGET GENES FOR THE HUMAN HOXD13 PROTEIN, INVOLVED IN SYNPOLYDACTYLY, USING A COMBINED CONDITIONAL EXPRESSION/PROMOTER TRAP APPROACH.

Pubblicazioni Scientifiche

• 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AME

  Cup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development

• 2001 JOURNAL OF BIOLOGICAL CHEMISTRY

  The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function

• 2004 DEVELOPMENT

  Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins

• 2003 DEVELOPMENT

  An 147L substitution in the HOXD13 homeodomain causes a novel human limb malformation by producing a selective loss of function

• 2002 Nucleic acids research

  Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors

• 1999 GENES & DEVELOPMENT

  The subcellular localization of PBX1 and EXD proteins depends on nuclear import and export signals and is modulated by association with PREP1 and HTH

• 2003 EMBO JOURNAL

  PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain